WebINCB13739 Summary The purpose of this study is to determine whether the investigational drug INCB013739 has an effect on systemic and adipose tissue 11-HSD1 activity in obese, insulin resistant subjects. Locations Inclusion Criteria » Male and female subjects between 18 years and 65 years of age. » BMI between 30 and 42 kg/m2, inclusive. WebINCB13739 (INCB-13739) is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) with high seelctivity over other dehydrogenases, glucocorticoid and mineralocorticoid …
New Incyte CCR5 Antagonist 14-Day Study Results - NATAP
WebDescription: INCB13739 is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) for the treatment of type 2 diabetes. INCB-13739 has high selectivity for 11beta-HSD1 over other … WebJun 7, 2006 · Incyte has initiated a Phase I clinical trial of INCB13739, an orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1). 11beta-HSD1 is an enzyme that appears to be critical to the development of Type 2 diabetes. florida state parks near beaches
Results Presented at the ADA 69th Scientific Sessions …
WebINCB 13739 Alternative Names:INCB013739; INCB13739 Latest Information Update: 02 Oct 2024 Price : $50 * Buy Profile Adis is an information provider. We do not sell or distribute … WebSep 26, 2007 · Incyte Corporation Reports Positive Proof-of-Concept Results For INCB18424, Its Lead JAK Inhibitor, and INCB13739, its Lead 11beta-HSD1 Inhibitor BioSpace Filter News All (765,123) Topic (723,893) Industry (144,579) Hotbed/Location (697,546) Career Advice (3,797) Employer Insights (226) Therapeutic Insights (973) WebNov 14, 2006 · A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. florida state parks on east coast