Higuchi and connors
WebThe shake-flask method is based on the phase solubility technique that was developed 40 years ago and is still the most reliable and widely used method for solubility measurement … WebAug 8, 2024 · The method of Higuchi and Connors proposes that to determine the inclusion constant of a formed complex 1H 4 MGF:1βCD, the phase-solubility diagram, ([H 4 MGF] = …
Higuchi and connors
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WebAug 8, 2024 · The method of Higuchi and Connors proposes that to determine the inclusion constant of a formed complex 1H 4 MGF:1βCD, the phase-solubility diagram, ( [H 4 MGF] = f ( [βCD])) of saturated solutions in mangiferin must show a linear trend and then equation ( 6) relates the slope ( α) and intercept ( G0) of the straight line with the equilibrium …
WebT. Higuchi, A. Connors Published 1965 Chemistry No Paper Link Available Save to Library Create Alert Cite 2,633 Citations Citation Type More Filters Development of Solvent-Free … WebMay 9, 2007 · A phase solubility study was performed, according to the method reported by Higuchi and Connors, to evaluate the changes of isoflavone in the complexation state and the obtained diagrams suggested that it forms complexes with a stoichiometry of 1:1.
WebDec 18, 2024 · Phase solubility test was performed according to the method of Higuchi and Connors [ 24 ]. An excess amount of camphor was added to aqueous CD (HPβCD and HPγCD) solutions, and the suspensions were shaken at RT. After equilibrium was achieved at the end of 48 h, the suspensions were filtered with 0.45 μm membrane filter. WebJan 30, 2024 · According to Higuchi and Connors (1965), the linear host-guest correlation can be classified as linear diagram (A L) type because the straight line had a slope of less than 1 in each compound, i.e., 0.0074, 0.0202 and 0.0266 for curcumin, demethoxycurcumin, and bisdemethoxycurcumin, respectively. The result indicated that one mole of ...
WebThis was explained by the solubilization theory of Higuchi and Connors. The solubility analysis of the ternary drug/competitor/CyD systems may be particularly useful for determination of the stability constant of a drug whose physicochemical and spectroscopic analyses are difficult, because they can be calculated by monitoring the solubility ...
WebPhase-solubility studies Water solubility studies for both triterpenic acids were conducted by the Higuchi and Connors method [16] using a series of increasing concentrations of … dyrehavsbakken theme parks scandinaviaWebSep 1, 2010 · The phase-solubility diagrams obtained according to the Higuchi and Connors method [6] allowed us to estimate the molar ratio and the apparent stability constants of … dyrell roberts coachWebPersonal papers of Takeru Higuchi, PP 359. University of Kansas. Kenneth Spencer Research Library. Higuchi and Connors, "Spectrophotometric Detection of the End Point in the Karl Fischer Titration of Water,", 1959, Box: 11, Folder: 110. Personal papers of Takeru Higuchi, PP 359. University of Kansas. Kenneth Spencer Research Library. csb ultrathin bibleWebThis was explained by the solubilization theory of Higuchi and Connors. The solubility analysis of the ternary drug/competitor/CyD systems may be particularly useful for … dyrell roberts virginia techWebMar 22, 2024 · We also introduced the Higuchi and Connors method to analyze inclusion complex formed through solubilization and the pharmaceutical benefits that can be gained using CDs. In addition, the practical applications of CDs in nasal, ophthalmic, pulmonary, and rectal drug delivery are also described. CD applications for drug solubilization dyre the strangerWebApr 7, 2024 · The most dramatic increase in solubility of curcumin was obtained more than 20 times higher by solidly dispersed complex of CUR with PEG 6000 (1:3) than its intrinsic solubility. Following the classification of Higuchi and Connors, CUR in different PEG 6000 solutions showed A N diagram. dyreon outsey obituaryWebJan 1, 2011 · T. Higuchi, K.A. Connors. Phase solubility techniques. Adv Anal Chem Instrum, 4 (1965), pp. 117-212. Google Scholar [18] L. Greenspan. Humidity Fixed Points of Binary Saturated Aqueous Solutions. J Res Nat Bur Stand, 81A (1) (1977), pp. 89-96. CrossRef Google Scholar [19] dyre the stranger ck3