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Nrf2 knockout dysregulates iron metabolism and ... - ScienceDirect
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WebOct 26, 2024 · Ferroptosis is an iron- and lipid peroxidation-dependent form of regulated cell death. The release of labile iron is one of the important factors affecting sensitivity to ferroptosis. Yes-associated protein (YAP) controls intracellular iron levels by affecting the transcription of ferritin heavy chain (FTH) and transferrin receptor (TFRC). However, … WebAntibodies employed for these analyses consist of SOD2 (Millipore), SDHB (Abcam), HMOX1 (Abcam), ALAS2 (Abcam), TFR1 (Abcam), FTH (Abcam), and -actin (Developmental Research Hybridoma Loan provider, The School of Iowa, Iowa Town). Quantitation of blots was performed utilizing ImageJ software program. Antioxidant … WebFTH was immunoblotted using anti-FTH antibodies and Fe 2+ levels were assayed using commercial kits (Abcam, ab83366). (D–F) the HeLa cells were pretreated with or without … jp morgan chase bank subpoena address